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Updated: Jul 12, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Reverse remodeling with resynchronization in an asymptomatic patient with dilated hypokinetic cardiomyopathy
Christophe D'Ivernois1, Laurent Deluche, Le Anh Tuan Nguyen
1Service de Cardiologie, Hôpital Universitaire Dupuytren, Limoges, France. christophe.divernois@chu-limoges.fr
Abstract:
Cardiac resynchronization therapy (CRT) is a validated treatment for selected heart failure patients who remain highly symptomatic despite optimal drug treatment. Yet there is currently no indication for CRT in patients with few or no symptoms. We report a spectacular "reverse remodeling" effect after CRT in an asymptomatic patient with hypokinetic dilated myocardiopathy who needed pacing for atrio-ventricular conduction disorder. CRT was chosen to prevent deterioration of left ventricular function by conventional right apical pacing. Thus, CRT could be indicated in patients with hypokinetic dilated myocardiopathy before the appearance of symptoms.
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