Related Experiment Video
Updated: Jul 12, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Gastrointestinal involvement in systemic sclerosis. An underestimated complication]
P Saar1, T Schmeiser, I H Tarner
1Abt. für Rheumatologie und klinische Immunologie, Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie der Justus-Liebig-Universität Giessen, Kerckhoff-KlinikBad Nauheim, Benekestrasse 2-8, 61231, Bad Nauheim, Germany. p.saar@kerckhoff-klinik.de
Systemic sclerosis (SSc) is an autoimmune disease causing fibrosis and immune system issues. Early diagnosis and monitoring of complications, especially gastrointestinal issues, are crucial for managing this rare condition.
Area of Science:
- Rheumatology and Immunology
- Dermatology
- Internal Medicine
Context:
- Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease.
- Characterized by progressive fibrosis, immune system abnormalities, and microcirculation changes.
- Affects skin and internal organs, necessitating interdisciplinary care.
Purpose:
- To highlight the challenges in managing Systemic Sclerosis.
- To emphasize the importance of early diagnosis and monitoring of complications.
- To address the frequent neglect of gastrointestinal involvement in SSc.
Summary:
- SSc presents with skin thickening, affecting internal organs in both limited and diffuse forms.
- Early detection and close monitoring of all complications are vital due to increased morbidity and mortality.
- Gastrointestinal involvement is often overlooked, leading to delayed treatment.
Impact:
- Improved patient outcomes through timely diagnosis and comprehensive management.
- Enhanced awareness among physicians regarding the multifaceted nature of SSc.
- Reduced morbidity and mortality associated with Systemic Sclerosis.
Related Concept Videos
Inflammatory Bowel Disease IV: Clinical Manifestations
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease III: Crohn's Disease
Other Disorders of Digestive System
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
