Decrease in binding for the neuropeptide VIP in response to marked inflammation of the mucosa in ulcerative colitis.

Maria Jönsson1, Orjan Norrgård, Magnus Hansson

  • 1Department of Integrative Medical Biology, Anatomy, Umeå University, SE-901 87 Umeå, Sweden. maria.jonsson@anatomy.umu.se

Summary

Vasoactive intestinal peptide (VIP) binding decreases in inflamed intestinal tissues of ulcerative colitis patients. This reduction may impair VIP's beneficial effects in severe inflammation.

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