Related Experiment Video
Updated: Aug 8, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
Published on: February 2, 2014
Angiolymphoid hyperplasia with eosinophilia successfully treated with imiquimod. A case report
Gulsum Gencoglan1, Semsettin Karaca, Banu Ertekin
1Dermatology Department, Afyon Kocatepe University Medical School, Afyon, Turkey. gencoglan75@hotmail.com
Abstract:
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disorder characterized by vascular proliferation, eosinophilia in peripheral blood samples and lymphocytosis. The etiology is unknown; this rare condition is generally seen in women. It often presents as multiple, grouped red nodules in the periauricular region, scalp line and neck. Numerous therapeutic approaches have been tried for ALHE including destructive techniques such as electrodesiccation, cryotherapy, surgical excision, radiotherapy or laser (argon, CO(2), pulse dye). We present an ALHE case that was treated successfully by using topical imiquimod cream.
