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Construction of the zona pellucida during production of fertilizable mouse eggs

P M Wassarman1

  • 1Department of Cell and Developmental Biology, Roche Institute of Molecular Biology, Nutley, New Jersey 07110.

Bulletin De L'Association Des Anatomistes
|March 1, 1991
PubMed

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Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...