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Updated: Jul 11, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Traumatic brain injury
William Heegaard1, Michelle Biros
1Department of Emergency Medicine, Hennepin County Medical Center, University of Minnesota Medical School, 701 Park Avenue S, Minneapolis, MN 55415, USA. emdoc@yahoo.com
Abstract:
Traumatic brain injury (TBI) is a significant source of morbidity and mortality throughout the world. This article discusses the epidemiology, pathophysiology, and clinical presentations of minor, moderate, and severe TBI. Controversial topics, such as hypertonic saline for increased intracranial pressure, prehospital intubation of patients who have experienced TBI, and the use of recombinant factor VIIa, are addressed.
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