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Related Experiment Videos

[Treatment with retinoids].

P Berbis1

  • 1Clinique dermatologique, Hôtel-Dieu, Marseille.

La Revue Du Praticien
|October 15, 1991
PubMed
Summary
This summary is machine-generated.

Aromatic retinoids, like acitretin, effectively treat severe psoriasis by regulating skin cell growth and modulating immune responses. However, they have side effects and are strictly contraindicated in pregnancy due to teratogenicity.

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Area of Science:

  • Dermatology
  • Pharmacology

Context:

  • Psoriasis is a chronic inflammatory skin condition.
  • Severe psoriasis requires effective therapeutic agents.

Purpose:

  • To review the properties, indications, and management of aromatic retinoids for psoriasis.
  • To highlight the efficacy and safety considerations of etretinate and acitretin.

Summary:

  • Aromatic retinoids are synthetic vitamin A derivatives with epidermal differentiation regulating and immunomodulating effects.
  • Available agents include etretinate and acitretin, indicated for pustular, erythrodermic, and extensive psoriasis vulgaris.
  • Common side effects involve skin and mucous membranes; regular laboratory monitoring is essential.

Impact:

Related Experiment Videos

  • Aromatic retinoids offer significant treatment options for severe psoriasis.
  • Strict contraindication in pregnancy due to teratogenicity necessitates effective contraception.