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Recent advances in liquid chromatography-mass spectrometry and capillary zone electrophoresis-mass spectrometry for
M J Suter1, B B DaGue, W T Moore
1Analytical Chemistry Center, University of Texas Medical School, Houston 77225.
Journal of Chromatography
|August 16, 1991
Abstract:
The utility of the combination of separations techniques, such as liquid chromatography and capillary zone electrophoresis, with mass spectrometry in applications involving protein analysis is discussed. The use of continuous-flow fast atom bombardment and electrospray ionization mass spectrometry is compared for the analysis of tryptic digests. For liquid chromatography, both microbore and slurry-packed capillary bore columns were used to separate peptides from proteolytic digests.