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Published on: November 20, 2015
Bone disease of prematurity
1Neonatal Clinical Care Unit, King Edward Memorial Hospital for Women and Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia. mary.sharp@health.wa.gov.au
Early Human Development
|September 21, 2007
Summary
Bone disease of prematurity, a complication of preterm birth, requires adequate nutrition for treatment and prevention. Quantitative ultrasound shows promise for screening, though more research is needed for physical activity recommendations.
Area of Science:
- Neonatology
- Pediatric Endocrinology
- Nutritional Science
Background:
- Bone disease of prematurity is a significant complication affecting preterm infants.
- Understanding its etiology, treatment, and prevention is crucial for improving infant outcomes.
Purpose of the Study:
- To review the current understanding of bone disease of prematurity.
- To discuss effective nutritional strategies for management and prevention.
- To evaluate current and potential screening and monitoring tools.
Main Methods:
- Literature review of etiological factors.
- Analysis of nutritional requirements for bone health in preterm infants.
- Assessment of diagnostic and screening modalities, including quantitative ultrasound.
- Review of preventive strategies, including physical activity.
Main Results:
- Adequate nutrition (energy, protein, minerals) is essential for both treating and preventing bone disease.
- Screening methods are debated, but quantitative ultrasound shows potential for monitoring treatment response.
- Evidence for physical activity as a preventive measure is currently insufficient.
Conclusions:
- Optimal nutrition is the cornerstone of managing and preventing bone disease of prematurity.
- Quantitative ultrasound may serve as a valuable tool for screening and therapy monitoring.
- Further research is necessary to establish the role of physical activity in prevention.
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