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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Lacrimal sac melanoma.

Sumit Sitole¹, Chad A Zender, Amjad Z Ahmad

¹Department of Ophthalmology, Loyola University Medical Center, Maywood, Illinois, USA.

Ophthalmic Plastic and Reconstructive Surgery

|September 21, 2007

Summary

A rare malignant melanoma of the lacrimal sac presented as a medial canthus mass causing epiphora. Despite aggressive treatment including surgery, radiotherapy, and immunotherapy, the patient developed metastases, highlighting the neoplasm's aggressive nature.

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Published on: October 13, 2017

Area of Science:

Ophthalmology
Oncology
Pathology

Background:

Malignant melanoma of the lacrimal sac is an exceptionally rare neoplasm.
Early diagnosis and treatment are crucial for managing aggressive tumors in the ocular adnexa.

Observation:

A 48-year-old woman presented with a 5-month history of unilateral epiphora and a growing left medial canthus mass.
CT imaging revealed a soft tissue mass in the left lacrimal sac, causing nasolacrimal canal widening and erosion.

Findings:

Pathological confirmation identified the mass as malignant melanoma.
Despite wide surgical resection and adjuvant radiotherapy, the patient developed distant metastases to the chest wall.

Implications:

This case underscores the aggressive behavior of lacrimal sac melanoma.
Combined immunotherapy and chemotherapy represent a current treatment strategy for advanced disease.
Reviewing the clinical course and treatment strategies is vital for understanding and managing this rare malignancy.