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Updated: Jul 11, 2026
10:40
Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
Published on: December 22, 2017
CellMontage: similar expression profile search server
Wataru Fujibuchi1, Larisa Kiseleva, Takeaki Taniguchi
1Computational Biology Research Center, AIST Waterfront Bio-IT Research Building, 2-42 Aomi Koto-ku, Tokyo, Japan.
Bioinformatics (Oxford, England)
|September 27, 2007
Summary
CellMontage is a new tool for searching gene expression data across 69,000 microarray experiments. It finds similar expression profiles quickly, aiding biological research.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
Background:
- The proliferation of microarray databases necessitates advanced search functionalities.
- Existing tools may not efficiently handle the scale of modern gene expression data.
Purpose of the Study:
- To introduce CellMontage, a novel search engine for expression profile similarity.
- To provide efficient access to gene expression data within a large-scale database.
Main Methods:
- Development of a content-based search engine.
- Utilizing a database of 69,000 microarray experiments from NCBI's GEO.
- Implementing an algorithm for computing and displaying similar expression profiles.
Main Results:
- CellMontage enables similarity searches across a vast collection of microarray experiments.
- Search results for similar expression profiles are typically returned within 20 seconds.
- The core search engine software is available for download.
Conclusions:
- CellMontage offers a powerful and rapid solution for exploring gene expression data.
- This tool facilitates the discovery of biologically relevant patterns in large microarray datasets.
- The availability of the software promotes wider adoption and application in research.
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