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Epidemiology, pathophysiology, and prognosis of heart failure in the elderly
1Washington University School of Medicine, St. Louis, MO 63110, USA.
Insights
Heart failure is a primary condition linked to aging, impacting older adults significantly. Despite treatment advances, prognosis for heart failure in the elderly remains poor, with increasing prevalence expected.
Area of Science:
- Cardiology
- Gerontology
- Public Health
Background:
- Heart failure (HF) is intrinsically linked to cardiovascular aging.
- It arises from age-related physiological changes and increased cardiovascular disease risk in older individuals.
- HF prevalence and incidence escalate with age, posing a substantial societal burden.
Purpose of the Study:
- To highlight heart failure as a critical issue in aging populations.
- To underscore the persistent challenges in improving prognosis for older adults with HF.
- To project the future increase in HF cases among the elderly.
Main Methods:
- Review of epidemiological data on heart failure and aging.
- Analysis of current treatment outcomes for heart failure in older adults.
- Projection of future trends based on demographic shifts.
Main Results:
- Heart failure is a defining condition of cardiovascular aging.
- Despite therapeutic progress, median survival for older adults with HF is less than 5 years.
- The number of older individuals with HF is projected to rise substantially.
Conclusions:
- Heart failure presents a major challenge in geriatric cardiovascular medicine.
- There is an urgent need for improved strategies to manage heart failure in the aging population.
- The growing prevalence of HF in older adults necessitates proactive public health and clinical interventions.
Abstract:
Heart failure (HF) represents the quintessential disorder of cardiovascular aging, reflecting the convergence of age-related changes in the cardiovascular system and other organ systems and the increasing prevalence of cardiovascular diseases at older age. The prevalence and incidence of HF increase progressively with advancing age, and HF imposes an enormous burden on society in mortality, morbidity, and associated health care costs. Despite major advances in treatment of HF over the last 25 years, the prognosis remains poor, with median survival rates of less than 5 years in older adults. As the population ages, it is anticipated that the number of older people with HF will increase dramatically over the next several decades.
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