Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Increased ranging depth in optical frequency domain imaging by frequency encoding.

S M R Motaghian Nezam1, B J Vakoc, A E Desjardins

  • 1Harvard Medical School, Massachusetts General Hospital, MA 02114, USA. Motaghiannezam.Reza@mgh.harvard.edu

Optics Letters
|October 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optical coherence tomography.

Nature reviews. Methods primers·2023
Same author

Comparison of manual and semi-automatic registration in augmented reality image-guided liver surgery: a clinical feasibility study.

Surgical endoscopy·2020
Same author

Versatile and scalable fabrication method for laser-generated focused ultrasound transducers.

Optics letters·2020
Same author

Multicenter study on the diagnostic performance of multiframe volumetric laser endomicroscopy targets for Barrett's esophagus neoplasia with histopathology correlation.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2020
Same author

Expert assessment on volumetric laser endomicroscopy full scans in Barrett's esophagus patients with or without high grade dysplasia or early cancer.

Endoscopy·2020
Same author

Automated noise estimation in polarization-sensitive optical coherence tomography.

Optics letters·2020

This study presents a new optical frequency domain imaging (OFDI) method using dual reference arms to significantly improve ranging depth. The enhanced OFDI technique offers a threefold improvement in depth range compared to conventional methods.

Area of Science:

  • Optical Imaging
  • Biomedical Engineering
  • Metrology

Background:

  • Optical Frequency Domain Imaging (OFDI) is a powerful technique for high-resolution imaging.
  • Conventional OFDI techniques are limited by their ranging depth, restricting applications.
  • Improving ranging depth is crucial for advanced biomedical and industrial imaging.

Purpose of the Study:

  • To present a novel OFDI technique for enhanced ranging depth using frequency encoding.
  • To investigate the impact of dual reference arms with independent modulation frequencies on imaging performance.
  • To quantify the improvement in ranging depth and sensitivity compared to standard OFDI.

Main Methods:

  • Utilized two interferometer reference arms with distinct path lengths.

Related Experiment Videos

  • Employed independent modulation frequencies (25 MHz and 50 MHz) for each reference arm.
  • Analyzed the signal-to-cross-talk ratio based on frequency separation, tuning speed, wavelength, and coherence length.
  • Main Results:

    • Achieved a significant increase in ranging depth for OFDI.
    • Demonstrated a sensitivity decrease of only 6 dB over a 7 mm depth range.
    • Reported approximately a threefold improvement in ranging depth compared to conventional OFDI.

    Conclusions:

    • The proposed frequency-encoded OFDI technique effectively enhances ranging depth.
    • Dual reference arms with independent modulation frequencies are key to the improved performance.
    • The findings provide a foundation for advanced optical imaging with extended depth penetration.