Related Experiment Video
Updated: Dec 21, 2025

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Automated noise estimation in polarization-sensitive optical coherence tomography
Abstract:
Advanced signal reconstruction in polarization-sensitive optical coherence tomography (OCT) frequently relies on an accurate determination of the signal noise floor. However, current methods for evaluating the noise floor are often impractical and subjective. Here we present a method using the degree of polarization uniformity and known speckle intensity statistics to model and estimate the OCT noise floor automatically. We establish the working principle of our method with a series of phantom experiments and demonstrate the robustness of our noise estimation method across different imaging systems and applications in vivo.
More Related Videos
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

