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Updated: Jul 11, 2026
14:51
Comprehensive Workflow of Mass Spectrometry-based Shotgun Proteomics of Tissue Samples
Published on: November 13, 2021
Elemental mass spectrometry for quantitative proteomics.
Alfredo Sanz-Medel1, María Montes-Bayón, María del Rosario Fernández de la Campa
1Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, C/Julián Clavería 8, 33006, Oviedo, Spain. asm@uniovi.es
Analytical and Bioanalytical Chemistry
|October 3, 2007
Summary
Mass-spectrometry-based proteomics is a vital tool in biology. This review covers analytical methods using elemental mass-spectrometric detection for quantitative proteomic analysis.
Area of Science:
- Proteomics
- Analytical Chemistry
- Systems Biology
Background:
- Mass-spectrometry-based proteomics has become essential in molecular and cellular biology.
- Its application is rapidly expanding into systems biology.
Purpose of the Study:
- To review the evolution of analytical methods for quantitative proteomic analysis.
- To highlight the potential of elemental mass-spectrometric detection in proteomics.
Main Methods:
- Review of analytical methods in mass-spectrometry-based proteomics.
- Focus on elemental mass-spectrometric detection techniques.
Main Results:
- Detailed summary of the advancements in mass spectrometry for proteomics.
- Exploration of quantitative proteomic analysis using elemental detection.
Conclusions:
- Mass spectrometry is a powerful tool for quantitative proteomic analysis.
- Elemental mass-spectrometric detection offers significant potential for future proteomic studies.
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