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Updated: Jul 11, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
Published on: August 1, 2013
Exploiting dendritic cells for active immunotherapy of cancer and chronic infections
David W O'Neill1, Nina Bhardwaj
1Pathology, New York University School of Medicine, Rusk Research Bldg., Room 718, 400 East 34th Street, NewYork, NY 10016, USA. david.o'neill@med.nyu.edu
Abstract:
Dendritic cells (DCs) are important antigen-presenting cells (APCs) that can prime naive T cells and control adaptive immune responses with respect to magnitude, memory and self-tolerance. Understanding the biology of these cells is central to the development of new generation immunotherapies for cancer and chronic infections. This review presents a brief overview of DC biology and of the preparation and use of DC-based vaccines.
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