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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
[Immunization guidelines in patients with chronic liver diseases]
Florian Bihl1, Antoine Hadengue, Claire-Anne Siegrist
1Service de gastroentérologie et hépatologie, HUG, 1211 Genève 14.
Abstract:
Patients with chronic liver diseases and specially with cirrhosis have an impaired immune system and are vulnerable to viral (co-) infections. Vaccination against hepatitis A and B virus (HAV, HBV) is recommended for all patients with chronic liver diseases. However, the efficacy of vaccinations in patients with end-stage liver diseases and transplant recipients is disappointing. As soon as a chronic liver disease is diagnosed patients should be immunized with the common vaccines (flu and pneumoccocci). Due to reduced seroconversion rates, antibody levels should be tested after a booster vaccination.
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