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Related Experiment Video

Updated: Jul 11, 2026

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
05:05

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy

Published on: November 29, 2018

[Radiation induced breast sarcoma: a case report].

M Jerbi1, S Hidar, N Hattab

  • 1Service de gynécologie-obstétrique, CHU Farhat-Hached, 40002 Sousse, Tunisie. mehdijerbi@yahoo.fr

Gynecologie, Obstetrique & Fertilite
|October 9, 2007
PubMed
Summary

Radiation-induced breast sarcoma is a rare complication. This case highlights an undifferentiated sarcoma developing 8 years post-breast-conserving treatment, necessitating a mastectomy.

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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Summaries of the papers of the 4th National Congress of the Tunisian Society of Medical Oncology attached to the 4th Maghreb Congress of Oncology.

La Tunisie medicale·2018

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Background:

  • Breast-conserving treatment (BCT) is a standard breast cancer therapy.
  • Radiation therapy is a key component of BCT.
  • Late complications of radiation treatment can occur years after initial therapy.

Observation:

  • A patient developed an undifferentiated sarcoma.
  • The sarcoma occurred 8 years after receiving breast-conserving treatment.
  • The tumor involved the pectoralis major muscle.

Findings:

  • Radiation-induced breast sarcoma is a recognized but infrequent late complication.
  • The case demonstrates sarcoma development long after radiation exposure.
  • Surgical intervention, including mastectomy and pectoralis major resection, was required.

Related Experiment Videos

Last Updated: Jul 11, 2026

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
05:05

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy

Published on: November 29, 2018

Implications:

  • Awareness of potential late sarcomatous transformation is crucial for clinicians managing breast cancer survivors.
  • Long-term surveillance may be warranted for patients treated with radiation.
  • This case underscores the importance of considering rare complications in the differential diagnosis of post-radiation masses.