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Basidiobolomycosis: a case report.

A L Bittencourt1, S M Arruda, J A de Andrade

  • 1Department of Pathology, Hospital Univ. Prof. Edgard Santos, Federal University of Bahia, Brazil.

Pediatric Dermatology
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

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A rare pediatric subcutaneous entomophthoromycosis case caused by Basidiobolus haptosporus showed extensive ulceration and necrosis. Treatment with potassium iodide and ketoconazole successfully cured the lesion, highlighting an effective therapeutic approach.

Area of Science:

  • Mycology
  • Dermatology
  • Pediatrics

Background:

  • Subcutaneous entomophthoromycosis is a rare fungal infection.
  • Basidiobolus haptosporus is an emerging cause of this infection, particularly in children.
  • Typical presentations involve subcutaneous nodules or plaques.

Observation:

  • A five-year-old child presented with extensive ulceration and caseation necrosis.
  • The lesion exhibited an unusual, aggressive clinical course.
  • Initial treatment with potassium iodide alone was ineffective.

Findings:

  • The diagnosis was confirmed as subcutaneous entomophthoromycosis due to Basidiobolus haptosporus.
  • The patient showed a lack of response to conventional potassium iodide therapy.
  • A combination therapy of potassium iodide and ketoconazole led to complete lesion resolution.

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Implications:

  • This case expands the clinical spectrum of Basidiobolus haptosporus infections.
  • It underscores the importance of considering aggressive fungal infections in pediatric dermatology.
  • Combination therapy with ketoconazole may be a viable alternative for refractory cases.