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Updated: Jul 11, 2026
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Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
Published on: May 16, 2019
[Transient zinc deficiency in preterm infants]
1Universitäts-Hautklinik, Klinikum der Eberhard Karls Universität, Liebermeisterstrasse 25, 72076 Tübingen, Deutschland.
Summary
Preterm infants are susceptible to zinc deficiency due to negative zinc balance. This case study shows a preterm infant with zinc deficiency who rapidly improved with oral zinc supplementation.
Area of Science:
- Biochemistry
- Pediatrics
- Nutritional Science
Background:
- Zinc is a vital trace element crucial for numerous cellular processes and immune function.
- Preterm infants often experience a negative zinc balance, increasing their risk of deficiency.
- Symptomatic zinc deficiency can manifest with severe clinical symptoms.
Observation:
- A preterm infant presented with specific clinical signs indicative of zinc deficiency.
- Histological examination and laboratory tests confirmed the diagnosis of zinc deficiency.
- The infant's condition was monitored closely throughout the treatment period.
Findings:
- The preterm infant exhibited clear clinical manifestations of symptomatic zinc deficiency.
- Laboratory results and histological data corroborated the diagnosis.
- Treatment with oral zinc therapy led to a rapid and complete recovery.
Implications:
- Early diagnosis and intervention are critical for managing zinc deficiency in preterm infants.
- Oral zinc supplementation is an effective treatment for symptomatic zinc deficiency in this vulnerable population.
- This case highlights the importance of monitoring zinc status in preterm neonates to prevent severe health outcomes.
