Presumed infective meningoencephalitis complicated by bilateral optic neuritis

D M Gore1, G D Hildebrand, R Sekhri

  • 1Department of Ophthalmology, Great Ormond Street Hospital, London, UK. danielmgore@gmail.com

Insights

A severe case of presumed infective meningoencephalitis in a child led to bilateral optic neuritis. Prompt corticosteroid treatment improved vision and neurological deficits.

Area of Science:

  • Neurology
  • Ophthalmology
  • Infectious Diseases

Background:

  • Meningoencephalitis can present with diverse neurological complications.
  • Optic neuritis is a significant cause of visual impairment.

Observation:

  • A 7-year-old girl with presumed infective meningoencephalitis developed altered consciousness, hemiplegia, and severe bilateral optic neuritis.
  • Standard antimicrobial and antiviral therapies were ineffective.

Findings:

  • High-dose systemic corticosteroids were initiated due to the patient's deterioration.
  • The patient showed recovery of optic nerve function and resolution of hemiplegia after corticosteroid administration.

Implications:

  • This case highlights the potential for severe optic neuritis in meningoencephalitis.
  • Early and aggressive corticosteroid therapy may be crucial for preserving vision in such cases.
Abstract

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