Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bloodless FMRI.

Alan Jasanoff1

  • 1Departments of Nuclear Science and Engineering, Biological Engineering and Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. jasanoff@mit.edu

Trends in Neurosciences
|October 16, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Liposomal nanoprobes actuated by engineered water channels for sensitive detection of molecular targets by MRI.

Nature biomedical engineering·2026
Same author

Quantitative comparison of methods for widespread delivery of small molecules across the blood-brain barrier.

Communications biology·2026
Same author

A molecular probe for detecting cholinesterase activity in MRI.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Peripheral contributions to resting state brain dynamics.

Nature communications·2024
Same author

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo.

Advanced materials (Deerfield Beach, Fla.)·2024
Same author

Magnetic Detection of Neural Activity by Nanocoil Transducers.

Nano letters·2024
Same journal

Building neuroscience capacity in low- and middle-income countries: Lessons from Ghana.

Trends in neurosciences·2026
Same journal

Emulating the periodic table: A unified list of CNS terms and abbreviations for humans and experimental animals.

Trends in neurosciences·2026
Same journal

From chromatin dynamics to brain disease: Polycomb-Trithorax mechanisms in neurodevelopment.

Trends in neurosciences·2026
Same journal

Striatum regulates the cortex via the basal forebrain cholinergic system: A role for substance P.

Trends in neurosciences·2026
Same journal

A large brain adds new types of neurons: Molecular and functional signatures of spindle neurons in the human neocortex.

Trends in neurosciences·2026
Same journal

Exercise as a regulator of glymphatic function.

Trends in neurosciences·2026
See all related articles

Exploring non-hemodynamic functional imaging methods offers enhanced neuronal specificity for neuroscience research. These

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Biophysics

Background:

  • Conventional functional magnetic resonance imaging (fMRI) indirectly measures neural activity via hemodynamics.
  • This indirect measurement limits neuronal specificity and resolution in studying the nervous system.

Purpose of the Study:

  • To review recent developments in non-hemodynamic functional imaging methods.
  • To explore alternative approaches offering improved neuronal specificity over traditional fMRI.

Main Methods:

  • Review of diffusion-weighted functional imaging techniques.
  • Examination of methods for detecting neuronal electromagnetic fields.
  • Analysis of molecular imaging for neural metabolites and signaling species.

Related Experiment Videos

Main Results:

  • Non-hemodynamic methods aim for better resolution and neuronal specificity.
  • Progress is notable in diffusion-weighted, electromagnetic field detection, and molecular imaging.
  • 'Bloodless fMRI' approaches present unique advantages and disadvantages.

Conclusions:

  • Alternative functional imaging methods show promise for cognitive and systems neuroscience.
  • These 'bloodless fMRI' techniques offer new prospects for studying neural activity.
  • Further development is crucial for their application as experimental tools.