Related Experiment Video
Updated: Jul 10, 2026

08:47
Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
Published on: March 6, 2019
Synthesis of a promising immunosuppressant: FR252921
Dominique Amans1, Véronique Bellosta, Janine Cossy
1Laboratoire de Chimie Organique, ESPCI, Centre National de la Recherche Scientifique, 10 rue Vauquelin, Paris Cedex 05, France.
Organic Letters
|October 19, 2007
Abstract:
A concise and highly convergent synthesis of the promising immunosuppressant FR252921 was achieved by using optically active titanium complexes to control the configuration of the three stereogenic centers.

