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Updated: Jul 10, 2026
08:25
Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
[Hemolytic uremic syndrome by Streptococcus pneumoniae]
J D Herrero-Morín1, N Fernández, F Santos
1Sección de Nefrología Pediátrica, Departamento de Pediatría, Hospital Universitario Central de Asturias, Celestino Villami, Oviedo.
Nefrologia : Publicacion Oficial De La Sociedad Espanola Nefrologia
|October 20, 2007
Summary
Streptococcus pneumoniae can cause hemolytic uremic syndrome (HUS), a serious condition. Early diagnosis and specific transfusion strategies are crucial for better outcomes in these pediatric cases.
Area of Science:
- Nephrology
- Pediatrics
- Infectious Diseases
Background:
- Hemolytic uremic syndrome (HUS) is a severe condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury.
- While often associated with diarrhea, HUS can also arise from infections like Streptococcus pneumoniae.
Observation:
- A pediatric patient with Streptococcus pneumoniae pneumonia developed oliguric acute renal failure, anemia, and thrombocytopenia.
- The patient required intensive support including hemodiafiltration, blood product transfusions, and plasma infusions.
Findings:
- Pneumonia-associated HUS (S. pneumoniae HUS) presents higher morbidity and mortality than typical HUS.
- Recovery of renal function is common, but specific transfusion precautions are necessary.
Implications:
- Avoid IgM-containing blood products in S. pneumoniae-associated HUS to prevent adverse reactions.
- Prompt diagnosis of S. pneumoniae HUS is vital in children with systemic infections and acute kidney injury.
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