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Updated: Jul 10, 2026
07:28
Measurement of Bioelectric Current with a Vibrating Probe
Published on: January 4, 2011
Electrolyte pulse current measurements by CvMOS with microsecond and thermal voltage resolution.
Blake C Jacquot1, Nini Muñoz, Edwin C Kan
1Sch. of Electr. & Comput. Eng., Cornell Univ., Ithaca, NY 14853, USA. bcj7@cornell.edu
Summary
This study demonstrates fast electrolytic signal detection using chemoreceptive neuron MOS (CvMOS) transistors. This technology enables rapid DNA discrimination and external monitoring of cell action potentials for biosensing applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Non-invasive biosensing is crucial for real-time biological monitoring.
- Chemoreceptive neuron MOS (CvMOS) transistors offer potential for integrated biological sensing.
- Extended floating-gate structures enhance the performance of CvMOS transistors.
Purpose of the Study:
- To present fast electrolytic signal detection using CvMOS transistors.
- To explore the application of CvMOS transistors for DNA discrimination.
- To investigate the use of CvMOS transistors for monitoring cell action potentials.
Main Methods:
- Utilized non-invasive, charge-based sensing with CvMOS transistors.
- Employed an extended floating-gate structure.
- Performed fast electrolytic signal detection on silicon dioxide.
Main Results:
- Achieved fast detection of electrolytic signals on silicon dioxide.
- Demonstrated the potential for rapid DNA discrimination.
- Showcased the capability for external monitoring of cell action potentials.
Conclusions:
- CvMOS transistors with extended floating-gate structures facilitate efficient biological sensing.
- This technology advances rapid DNA analysis and cellular activity monitoring.
- The findings support system integration for advanced biosensing platforms.
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