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Updated: Jul 10, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Optical coherence tomography using rapidly swept lasers.
1Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA. syun@hms.harvard.edu
Optical coherence tomography (OCT) is a valuable diagnostic tool. A new generation, optical frequency domain imaging, promises to expand its medical uses.
Area of Science:
- Biomedical Optics
- Medical Imaging Technology
Background:
- Optical coherence tomography (OCT) is an established imaging modality with diverse clinical applications.
- Existing OCT technology provides high-resolution cross-sectional visualization of biological tissues.
Purpose of the Study:
- To introduce and highlight the potential of a second-generation OCT technology.
- To discuss the anticipated expansion of clinical applications driven by this advancement.
Main Methods:
- Review of emerging optical frequency domain imaging (OFDI) technology.
- Comparison of OFDI capabilities with conventional OCT.
Main Results:
- Optical frequency domain imaging represents a significant advancement over traditional OCT.
- This enhanced OCT technology is poised for broader clinical integration.
Conclusions:
- The development of optical frequency domain imaging is expected to significantly broaden the clinical utility of OCT.
- This next-generation OCT technology holds promise for revolutionizing diagnostic capabilities across various medical fields.
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