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Updated: Jul 10, 2026

RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes
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RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes

Published on: July 22, 2014

RNA editing in Trypanosoma brucei requires three different editosomes

Jason Carnes1, James Raffaello Trotter, Adam Peltan

  • 1Seattle Biomedical Research Institute, 307 Westlake Ave N, Suite 500, Seattle, WA 98109, USA.

Molecular and Cellular Biology
|October 24, 2007
PubMed
Summary

Trypanosoma brucei utilizes three distinct RNA editosomes for uridylate editing. A newly identified endonuclease, KREPB2, is crucial for editing cytochrome oxidase II mRNA and parasite survival.

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