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Updated: Jul 10, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Short bowel syndrome after continence-preserving procedures
Jon S Thompson1, Richard Gilroy, Debra Sudan
1Department of Surgery (General Surgery and Transplant Surgery), University of Nebraska Medical Center, 983280, Nebraska Medical Center, Omaha, NE 68198-3280, USA. jthompso@unmc.edu
Summary
Short bowel syndrome (SBS) can occur after continence-preserving surgeries for ulcerative colitis or familial polyposis. Desmoid tumors in familial polyposis patients undergoing resection alone have a poor prognosis, suggesting a need for earlier intestinal transplantation.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Abdominal Surgery
Background:
- Short bowel syndrome (SBS) is a potential complication of various conditions, including postoperative issues and malignancy.
- Continence-preserving operations for ulcerative colitis (UC) and familial polyposis (FAP) can lead to high morbidity and future malignancy risks.
Purpose of the Study:
- To investigate the causes and consequences of SBS in patients who have undergone continence-preserving procedures.
- To evaluate outcomes for patients with SBS following pelvic procedures or continent ileostomies.
Main Methods:
- Retrospective analysis of 24 patients (18-64 years) diagnosed with SBS after continence-preserving surgeries.
- Data collection included procedure type, ostomy status, remnant bowel length, underlying diagnosis, complications, and long-term outcomes.
- Follow-up ranged from 6 to 192 months.
Main Results:
- Thirteen of 24 SBS patients required long-term parenteral nutrition (PN).
- Four FAP patients with desmoid tumors died; one UC patient died post-intestinal transplant.
- Complications included Crohn's disease in UC patients, obstruction, mesenteric ischemia, and adenocarcinoma in a continent ileostomy.
Conclusions:
- SBS can develop after continence-preserving procedures, particularly with inflammatory bowel disease (IBD) or complications.
- SBS associated with desmoid tumors in FAP patients has a poor prognosis with resection alone.
- An aggressive approach, including earlier intestinal transplantation, may be warranted for select SBS patients.
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