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Updated: Jul 10, 2026

Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients
Published on: July 16, 2018
Big ligands for stabilization of small functionalities in calcium chemistry
Christian Ruspic1, Sjoerd Harder
1Anorganische Chemie, Universität Duisburg-Essen, Universitätsstrasse 5-7, 45117 Essen, Germany.
Abstract:
Reaction of (DIPP-nacnac)CaN(SiMe3)2.THF (DIPP-nacnac=CH{(CMe)(2,6-iPr2C6H3N)}2) with NH3 gave the heteroleptic complex (DIPP-nacnac)CaNH2.(NH3)2 which crystallized as a dimer with bridging NH2- ions. In contrast to other heteroleptic (DIPP-nacnac)calcium amides, (DIPP-nacnac)CaNH2.(NH3)2 is remarkably stable toward ligand exchange. Reaction of (DIPP-nacnac)CaH.THF with Me3SiCN gave the heteroleptic complex (DIPP-nacnac)CaCN.THF that crystallized as a trimer. The CN- ions bridge in a linear fashion between the Ca2+ ions. In a new synthetic route (DIPP-nacnac)CaN(SiMe3)2.THF reacted with Et3NH+Cl- to give (DIPP-nacnac)CaCl.THF, which crystallized as a dimer with bridging Cl- ions. The exceptional stability of these aggregates toward ligand-exchange reactions, which would give insoluble homoleptic Ca(NH2)2, Ca(CN)2, or CaCl2, is remarkable and likely due to their multinuclear nature.
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