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Updated: Jul 10, 2026

Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
[Interferon-stimulating activity of muramoyl dipeptide glycosides]
Abstract:
The uninvestigated interferon (IFN)-inducing capacity of glycoside derivatives of N-acetylmuramoyl-L-alanyl-D-isoglutamine (MDP) has been studied. Most MDP glycosides tested in vitro were more active than the reference preparation MDP. Under the in vivo conditions three studied preparations: MDP, a-heptyl-MDP and beta-(2-methyl-3-phenylchromonyl-7)-MDP stimulated production of considerable amount of circulating IFN that evidences for the promising character of their further investigation as preparations immunostimulators.
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