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Updated: Jul 10, 2026

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
08:06

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

Is energy deficiency good in moderation?

Christoph Freyer1, Nils-Göran Larsson

  • 1Department of Laboratory Medicine, Karolinska Institutet, 141 86, Stockholm, Sweden.

Cell
|November 6, 2007
PubMed
Summary

Reduced mitochondrial oxidative phosphorylation protects mice from obesity and diabetes. This suggests that impaired oxidative phosphorylation in insulin-resistant humans may be a compensatory mechanism, not a cause of diabetes.

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