Detection of DNA copy-number alterations in complex genomes using array comparative genomic hybridization.

Wei-Wen Cai1

  • 1Department of Molecular and Human Genetics, Houston, TX, USA.

Summary

Array-based comparative genomic hybridization (array CGH) offers powerful genomic insights. This study details an improved array CGH technology and protocols for bacterial artificial chromosome microarrays, successfully detecting DNA copy-number alterations in human and mouse samples.

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