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[The relationship between QRS voltage on ECG (the Minnesota code) and cardiac mortality amongst males. The Reykjavik
Steinunn Thordardottir1, Thor Aspelund, Arni Grimur Sigurdsson
1Landspitali, Háskóla Islands. steintho@landspitali.is
Insights
Electrocardiogram (ECG) voltage criteria for left ventricular hypertrophy (LVH) show limited ability to predict cardiac mortality in men. Larger QRS voltages on ECG are not a strong indicator of increased risk for heart disease death.
Area of Science:
- Cardiology
- Electrocardiography
- Public Health
Context:
- Left ventricular hypertrophy (LVH) is a significant clinical finding linked to adverse cardiovascular outcomes.
- Traditional ECG voltage criteria are used to diagnose LVH.
- The predictive value of these criteria for coronary heart disease (CHD) mortality requires further investigation.
Purpose:
- To evaluate the efficacy of standard ECG voltage criteria in predicting CHD mortality in males.
- To identify optimal QRS voltage thresholds that balance sensitivity and specificity for mortality prediction.
Summary:
- A population-based cohort study analyzed males diagnosed with LVH via ECG (Minnesota code) and a control group.
- ECG voltage criteria were systematically refined to assess their correlation with CHD mortality.
- No significant difference in CHD mortality was observed between males meeting standard LVH criteria and controls.
Impact:
- The study indicates a limited correlation between high QRS voltage on ECG and mortality risk in males.
- QRS voltage alone is an insufficient predictor of cardiac mortality.
- Findings suggest a need for improved risk stratification tools beyond basic ECG voltage measurements.
Objective:
Left ventricular hypertrophy (LVH) is important clinically because it is associated with heart failure, arrhythmia, myocardial infarction and stroke. The purpose of this study was to assess how well traditional ECG voltage criteria predict coronary heart disease mortality amongst males and to find the QRS voltages that best combine sensitivity and specificity in this sense.
Material And Methods:
Our study is a random population cohort study initiated in 1967. The study group included males that had been diagnosed with LVH on ECG using the Minnesota code (n=206). The other male participants of the study (n=8595) comprised the control group. The ECG voltage criteria of the Minnesota code were systematically narrowed and the mortality of those who fulfilled the stricter criteria compared with those who did not.
Results:
There was no significant increase in coronary heart disease mortality difference between those who fulfilled the criteria of the Minnesota code for LVH and those who did not. When the criteria were narrowed there was a trend towards increased mortality with larger QRS voltages, but the trend was not strong.
Conclusion:
The correlation between large QRS voltage on ECG and mortality in males is limited. QRS voltage is an imperfect tool for prediction of cardiac mortality amongst males.
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