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Updated: Jul 10, 2026
05:21
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
[Influenza: a current medical problem]
Ivanko Bojić1, Olga Dulović, Eleonora Gvozdenović
1Specijalisticka ordinacija Dr Bojić", Beograd. drbojic@net.yu
Medicinski Pregled
|November 10, 2007
Summary
Influenza A virus poses a significant global health threat, causing severe respiratory illness and pandemics. Vaccination strategies targeting current hemagglutinin and neuraminidase subtypes are crucial for prevention.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Context:
- Acute respiratory infections are common globally, with influenza viruses being a major cause.
- Type A influenza has caused three major pandemics in the last century, notably the 1918 and 1919 events, characterized by high mortality in young, healthy individuals due to severe pneumonia.
Purpose:
- To provide an overview of the clinical manifestations, laboratory findings, and radiographic features of influenza A.
- To discuss therapeutic interventions including symptomatic, supportive, antiviral, and corticosteroid treatments.
Summary:
- Avian influenza A outbreaks, like the one in Southeast Asia (2003-2004), highlight the potential for zoonotic transmission to humans, with a high fatality rate and interhuman transmissibility.
- The review covers clinical presentation, diagnostic findings, and treatment options for influenza A.
Impact:
- Emphasizes the critical importance of vaccines containing hemagglutinin and neuraminidase subtypes relevant to circulating influenza strains for effective disease control.
- Informs clinical practice and public health strategies for managing and preventing influenza A epidemics and pandemics.
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