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Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
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The two-component system sivS/R regulates virulence in Streptococcus iniae.

Shelly Bolotin1, Jeffrey D Fuller, Darrin J Bast

  • 1Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

FEMS Immunology and Medical Microbiology
|November 10, 2007
PubMed
Summary

The SivS/R system in Streptococcus iniae controls virulence and gene expression. Deleting SivS/R reduces bacterial virulence and affects surface protein levels, impacting disease potential.

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