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Postmenopausal vaginitis.

Paul Nyirjesy1

  • 1Department of Obstetrics and Gynecology, Drexel University College of Medicine, 245 North 15th Street, New College Building, 16th Floor, Philadelphia, PA 19102, USA. pnyirjes@drexelmed.edu

Current Infectious Disease Reports
|November 15, 2007
PubMed
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Vaginitis in postmenopausal women is rising. Estrogen decline alters vaginal flora, decreasing Lactobacillus and increasing susceptibility to infections like bacterial vaginosis and vulvovaginal candidiasis.

Area of Science:

  • Gynecology
  • Menopause Research
  • Microbiome Studies

Background:

  • Aging US population increases the incidence of vaginitis in postmenopausal women.
  • Estrogen withdrawal significantly alters the vaginal environment.
  • Changes include decreased Lactobacillus dominance and altered Candida colonization.

Purpose of the Study:

  • To review the changing landscape of vaginitis in postmenopausal women.
  • To highlight the relative increase in less common conditions.
  • To note the unknown effects of exogenous estrogen on menopausal vaginitis.

Main Methods:

  • Literature review focusing on postmenopausal vaginitis.
  • Analysis of changes in vaginal flora post-menopause.
  • Comparison of common and less common vaginitis etiologies.

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Main Results:

  • Common infections like bacterial vaginosis and vulvovaginal candidiasis may occur less frequently.
  • Desquamative inflammatory vaginitis and lichen sclerosus gain relative importance.
  • The impact of exogenous estrogen on these conditions is not well-understood.

Conclusions:

  • Vaginitis management in postmenopausal women requires attention to age-related changes.
  • Less common conditions become more significant in this demographic.
  • Further research is needed on the role of estrogen therapy.