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A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Dietary fat for infants with enterostomies
William F Malcolm1, Robert W Lenfestey, Henry E Rice
1Department of Pediatrics, Duke University, Durham, NC 27710, USA. malco002@mc.duke.edu
Journal of Pediatric Surgery
|November 21, 2007
Summary
Adding dietary lipids to enteral feedings significantly reduced ostomy output and improved weight gain in infants with short bowel syndrome (SBS). This intervention shows promise for managing infants with enterostomies and limiting related complications.
Area of Science:
- Pediatric Gastroenterology
- Neonatal Nutrition
- Surgical Neonatology
Background:
- Infants with enterostomies often exhibit symptoms of short bowel syndrome (SBS).
- High ostomy output and poor weight gain are common challenges in these infants.
Purpose of the Study:
- To evaluate the impact of dietary lipids on ostomy output.
- To assess the effect of dietary lipids on weight gain in infants with enterostomies.
Main Methods:
- Retrospective review of 10 neonates with temporary enterostomies due to necrotizing enterocolitis or intestinal perforations.
- Administration of a soluble dietary fat supplement added to enteral feedings.
- Comparison of ostomy output (% of intake) and daily weight gain before and after lipid supplementation.
Main Results:
- Ostomy output decreased by 32% (from 29.3% to 19.8% of intake, P < .05).
- Daily weight gain increased significantly from 7.7 g/d to 26.8 g/d (P < .01).
- Infants with higher initial ostomy output (>20%) showed the most benefit.
Conclusions:
- Dietary lipids effectively reduce ostomy output and enhance weight gain in infants with enterostomies and SBS.
- Lipid supplementation may be a valuable strategy to mitigate morbidity in infants with enterostomies.
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