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Updated: Jul 10, 2026
09:39
Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells
Published on: July 29, 2016
Hypermetropia and esotropia in myotonic dystrophy
Kathryn E Bollinger1, Valerie Kattouf, Brian Arthur
1Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Summary
Myotonic dystrophy patients frequently exhibit hypermetropia and strabismus. Early ophthalmic exams are crucial for managing these common vision issues in children with myotonic dystrophy.
Area of Science:
- Ophthalmology
- Genetics
- Pediatrics
Background:
- Myotonic dystrophy is a multisystemic genetic disorder.
- Ocular manifestations are common in myotonic dystrophy patients.
Purpose of the Study:
- To review detailed ophthalmic examinations of myotonic dystrophy patients.
- To assess refractive error and ocular alignment in this population.
Main Methods:
- Retrospective chart review of 32 patients (27 children, 5 adults) with myotonic dystrophy.
- Analysis of detailed ophthalmic examination data.
Main Results:
- 86% of eyes were hypermetropic.
- Average hypermetropia was +6.0 D in children and +2.10 D in adults.
- 56% of children had esotropia, and 22% had amblyopia.
Conclusions:
- Children with myotonic dystrophy require comprehensive eye exams.
- Emphasis should be on recognizing and managing hypermetropia and strabismus.
- Early intervention can improve visual outcomes.
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