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Updated: Jul 10, 2026

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
Photochemical synthesis of R-shaped DNA via 5-cyanovinyldeoxyuridine
Masayuki Ogino1, Kenzo Fujimoto
1The School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.
Abstract:
We now report template-directed photoligation using ODN containing alpha(C)U and beta(C)U at both terminal ends. By using this method, we performed template-directed photoligation in two positions at the middle of DNA and synthesized R-shaped DNA as novel structure. The isolated R-shaped DNA was characterized by MALDI-TOF MS and enzymatic digestion.
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