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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Improving the quality of medical prescriptions in neonatal units
Carmen R Pallás1, Javier De-la-Cruz, M Teresa Del-Moral
1Neonatal Unit, Hospital Universitario 12 de Octubre, Madrid, Spain. jakeka1@movistar.net
Insights
Medication errors in neonatal intensive care units significantly decreased after implementing a training program and a digital dosage calculation system. This intervention improved the quality of prescriptions for newborns, enhancing patient safety.
Area of Science:
- Neonatal medicine
- Pediatric pharmacology
- Healthcare quality improvement
Background:
- Neonatal units are highly susceptible to medication errors, with failures often occurring during prescription and preparation.
- Prescribing errors pose a significant risk to vulnerable infant populations.
Purpose of the Study:
- To assess the prevalence of prescribing practice violations before and after implementing quality improvement measures.
- To evaluate the impact of targeted interventions on medication prescription accuracy in neonates.
Main Methods:
- A before-and-after evaluation study was conducted in a tertiary neonatal unit.
- Analysis of 6,320 handwritten prescriptions (pre-intervention) and 1,435 (post-intervention).
- Interventions included prescriber training and a pocket PC-based automatic dosage calculation system.
Main Results:
- The proportion of incorrect prescriptions dropped from 39.5% to 11.9% post-intervention (Prevalence Ratio: 0.29).
- Prescriptions with multiple errors decreased from 11.1% to 1.3% (Prevalence Ratio: 0.09).
Conclusions:
- Violations of good prescribing practice are prevalent in neonatal settings.
- A straightforward intervention significantly enhances the quality of handwritten medical prescriptions for neonates in intensive care.
Background:
Pediatric units, especially neonatal units, are highly vulnerable to error generally and to medication error in particular. Potential failures are distributed across the entire medication process, occurring mostly at the time of medication prescription and during preparation for drug administration.
Objective:
To estimate the prevalence of violations of good prescribing practice before and after the implementation of several measures aimed at improving the quality of the medical prescription.
Methods:
Before and after evaluation study with prospective data collection in a third level neonatal unit. 6,320 handwritten medical prescriptions for neonates admitted in the first study period and 1,435 in the second period were analyzed. Training on good prescribing practice and the implementation of a pocket PC-based automatic dosage calculation system were the interventions. The main outcome measure was the proportion of prescriptions with violations of good prescribing practice: incorrect dose, units, dose interval, route of administration or legibility.
Results:
Incorrect prescriptions decreased from 39.5% before the intervention to 11.9% after, with an adjusted prevalence ratio of 0.29 (0.25-0.34). The number of wrongly specified items on a single prescription decreased from 11.1% of the prescriptions with two or more wrongly specified items in the first period to 1.3% in the second period, with a prevalence ratio of 0.09 (0.05-0.14).
Conclusions:
Violations of good prescribing practice are common in neonatal units. A simple intervention should improve the quality of handwritten medical prescriptions for newborns admitted to intensive care settings.
Related Concept Videos
Guidelines for Nursing Documentation I
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
Factors Affecting Drug Response: Overview
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmaceutical Poisoning: Potential Scenarios

