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A visual framework for classifying adaptive design clinical trials using the GATE frame and PICO terminology

David Lora1,2,3, Antonio Lalueza Blanco1,4,5,6, Guillermo Maestro de la Calle5,7

  • 1Instituto de Investigación Sanitaria del Hospital Universitario 12 de Octubre (imas12), Madrid, Spain.

Dialogues in Health
|June 15, 2026
PubMed

Keywords:
Adaptive designCONSORT adaptiveCOVID-19Clinical trialPICO terminologyPublic health preparednessTeaching tool

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