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Updated: Jul 9, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Retinal vein occlusions and mortality: the Beijing Eye Study
Liang Xu1, Wei W Liu, Ya X Wang
1Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Purpose:
To assess the association between retinal vein occlusion (RVO) and mortality in a population-based setting.
Design:
Population-based, longitudinal study.
Methods:
At baseline in 2001, the Beijing Eye Study examined 4,335 subjects for RVO with a frequency of detected vein occlusions of 61 (1.4%) in 4,335 subjects. In 2006, all study participants were invited for a follow-up examination.
Results:
Of the 4,335 subjects, 3,195 (73.7%) returned for follow-up examination, whereas 132 (3.0%) subjects had died and 1,008 (23.3%) subjects declined to be re-examined or had moved away. For the subjects younger than 70 years or than 65 years, respectively, RVO was associated significantly with an increased mortality rate (P = .05; 95% confidence interval [CI], 0.995 to 8.26; and P = .001; 95% CI, 2.11 to 18.73, respectively).
Conclusions:
RVO in relatively young persons may signal a significant risk of mortality.
