Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimization of optode arrangements for diffuse optical tomography: A singular-value analysis.

J P Culver, V Ntziachristos, M J Holboke

    Optics Letters
    |November 28, 2007
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nucleation kinetics and virtual melting in shear-induced structural transitions.

    Reports on progress in physics. Physical Society (Great Britain)·2024
    Same author

    Morphology and line tension of twist disclinations in a nematic liquid crystal.

    Soft matter·2024
    Same author

    Magnetic-field-driven director configuration transitions in radial nematic liquid crystal droplets.

    Physical review. E·2023
    Same author

    Direction-dependent dynamics of colloidal particle pairs and the Stokes-Einstein relation in quasi-two-dimensional fluids.

    Nature communications·2023
    Same author

    Raster-scanning optoacoustic mesoscopy biomarkers for atopic dermatitis skin lesions.

    Photoacoustics·2023
    Same author

    Depletion-driven antiferromagnetic, paramagnetic, and ferromagnetic behavior in quasi-two-dimensional buckled colloidal solids.

    The Journal of chemical physics·2023
    Same journal

    Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

    Optics letters·2026
    Same journal

    E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

    Optics letters·2026
    Same journal

    Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

    Optics letters·2026
    Same journal

    Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

    Optics letters·2026
    Same journal

    Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

    Optics letters·2026
    Same journal

    Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

    Optics letters·2026
    See all related articles

    We developed a method to optimize diffuse optical tomography (DOT) instrument resolution using singular-value analysis. This approach enhances device configuration for improved medical imaging, particularly in breast imaging applications.

    Area of Science:

    • Biomedical optics
    • Medical imaging
    • Image reconstruction

    Background:

    • Diffuse optical tomography (DOT) is a promising imaging modality.
    • Optimizing DOT instrument resolution is crucial for accurate image reconstruction.
    • Current methods for resolution assessment and optimization require enhancement.

    Purpose of the Study:

    • To develop a novel method for optimizing the spatial resolution of diffuse optical tomographic instruments.
    • To introduce singular-value analysis of the tomographic weight matrix as a measure of image resolution.
    • To demonstrate the utility of this method in optimizing device configuration for breast imaging.

    Main Methods:

    • Singular-value decomposition (SVD) of the tomographic weight matrix was employed.

    Related Experiment Videos

  • A resolution measure based on SVD was defined and monitored.
  • Device parameters, including spatial sampling interval and field-of-view, were optimized in a parallel-plane transmission geometry.
  • Resolution was compared between transmission and remission geometries.

    • Main Results:

    • Singular-value analysis effectively quantifies image resolution for DOT instruments.
    • Optimization of spatial sampling and field-of-view significantly improved image resolution.
    • Transmission geometry demonstrated comparable or superior resolution to remission geometry in specific configurations.

    Conclusions:

    • The proposed singular-value analysis method provides a robust approach to optimizing DOT instrument resolution.
    • This method facilitates enhanced image quality in diffuse optical tomography.
    • The findings are particularly relevant for advancing diffuse optical breast imaging technologies.