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Related Experiment Videos

Imaging needle for optical coherence tomography.

X Li1, C Chudoba, T Ko

  • 1Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Optics Letters
|December 11, 2007
PubMed
Summary
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We developed a miniature optical coherence tomography (OCT) imaging needle for interstitial imaging of tissues. This minimally invasive device enables high-resolution visualization of internal microstructures, aiding in procedures like OCT-guided biopsy.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Ophthalmology

Background:

  • Optical Coherence Tomography (OCT) is a valuable non-invasive imaging technique.
  • Current OCT probes often lack the miniaturization required for interstitial applications.
  • Minimally invasive imaging of solid tissues requires specialized probe designs.

Purpose of the Study:

  • To develop and demonstrate a miniature OCT imaging needle for interstitial tissue analysis.
  • To present a novel rotational coupler for efficient light delivery in a miniaturized OCT system.
  • To enable high-resolution, in vivo imaging of internal microstructures with minimal trauma.

Main Methods:

  • Design and fabrication of a miniature OCT imaging needle with a 27-gauge outer diameter.

Related Experiment Videos

  • Development of a novel rotational coupler using a glass capillary tube for fiber optic light coupling.
  • In vivo testing and demonstration of the OCT needle for interstitial imaging.

    • Main Results:

    • Successful development of a miniature OCT imaging needle capable of interstitial imaging.
    • Demonstration of micrometer-scale resolution imaging of internal tissue microstructures.
    • Successful in vivo imaging using the prototype OCT needle.
    • Integration potential with standard excisional biopsy devices for OCT-guided biopsy.

    Conclusions:

    • The miniature OCT imaging needle offers a minimally invasive approach for interstitial tissue imaging.
    • The developed device provides high-resolution visualization of internal microstructures.
    • This technology has significant potential for improving biopsy procedures and tissue analysis.