Related Experiment Video
Updated: Jul 9, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
[A 48-year-old woman's survival from a massive verapamil overdose]
Karina K Johansen1, Bo Belhage
1Bispebjerg Hospital, Anaestesiologisk Afdeling Z. karinakjohansen@hotmail.com
Abstract:
We present a case report of survival from a massive verapamil overdose. The patient, a 48-year-old female, was admitted 12 hours after suicidal ingestion of 10.08 grams of Isoptin Retard, a sustained release calcium channel blocker. On admittance, the patient had altered mental status, was hypotensive, and ECG showed bradycardia with nodal rhythm. The patient was treated with activated charcoal, colloids, crystalloids, norepinephrine, isoprenalin and epinephrine infusion, high dose glucose-insulin infusion and calcium. The patient was discharged for rehabilitation after two weeks.
More Related Videos
14:03High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers
Published on: March 24, 2023
10:01High-Throughput Optical Controlling and Recording Calcium Signal in iPSC-Derived Cardiomyocytes for Toxicity Testing and Phenotypic Drug Screening
Published on: March 31, 2022
Related Concept Videos
Pharmaceutical Poisoning: Treatment Strategies
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Drug Toxicity: Risk factors
Drug Toxicity: Overview
Drug Toxicity: Dose-Dependent Reactions
Drug Dosing: Geriatric Patients