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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

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A seminal finding for understanding HIV transmission.

Nadia R Roan1, Warner C Greene

  • 1Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. nroan@gladstone.ucsf.edu

Cell
|December 18, 2007
PubMed
Summary

Human semen contains a factor that dramatically increases human immunodeficiency virus (HIV) infectivity. This finding may explain the discrepancy between high HIV incidence and low in vitro infectivity.

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