An improved sensitivity non-enzymatic glucose sensor based on a CuO nanowire modified Cu electrode

Area of Science:

• Materials Science
• Electrochemistry
• Nanotechnology

Background:

• Glucose sensors are crucial for diabetes management.
• Developing sensitive and stable non-enzymatic glucose sensors is a key research area.
• Copper oxide (CuO) nanostructures show promise for electrochemical applications.

Purpose of the Study:

• To synthesize CuO nanowires for glucose sensor fabrication.
• To investigate the electrochemical properties of CuO nanowires for glucose oxidation.
• To evaluate the sensitivity, linearity, and detection limit of the developed glucose sensor.

Main Methods:

• Synthesis of Cu(OH)(2) nanowires followed by heat treatment to form CuO nanowires.
• Characterization using X-ray diffraction, X-ray photoelectron spectroscopy, SEM, and TEM.
• Electrochemical measurements of glucose oxidation at CuO nanowire modified electrodes in alkaline medium.

Main Results:

• CuO nanowires were successfully synthesized and characterized.
• Significantly reduced overpotential for glucose oxidation was observed at CuO nanowire electrodes.
• High sensitivity (0.49 microA/micromol dm(-3)), wide linear range (0.40 micromol dm(-3) to 2.0 mmol dm(-3)), and low detection limit (49 nmol dm(-3)) were achieved.
• The sensor demonstrated stability and fast amperometric response.

Conclusions:

• CuO nanowire modified electrodes enable highly sensitive, low potential, stable, and fast amperometric sensing of glucose.
• These findings highlight the potential of CuO nanowires for developing advanced non-enzymatic glucose sensors.