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Blue emission-dominated NaYbF4@NaYF4:2%Ho@NaYF4 upconversion nanoparticles for detecting ascorbic acid.

Pengli Wang1, Jiaxin Li1, Yujiao Zhang1

  • 1College of Chemistry, Sichuan University, Chengdu 610064, P. R. China. zcs@scu.edu.cn.

Nanoscale
|September 10, 2024
PubMed
Summary
This summary is machine-generated.

We developed novel upconversion nanoparticles (UCNPs) for sensitive ascorbic acid (AA) detection. These nanoparticles exhibit enhanced blue emission, enabling a new nanosensing platform for AA detection with a low detection limit.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Upconversion nanoparticles (UCNPs) offer unique optical properties for sensing applications.
  • Controlling the emission of UCNPs, particularly in the visible spectrum, is crucial for developing sensitive detection platforms.
  • Ascorbic acid (AA) is an important biomarker, and sensitive detection methods are needed.

Purpose of the Study:

  • To design and synthesize blue emission-dominated NaYbF4@NaYF4:2%Ho@NaYF4 (CSS) upconversion nanoparticles (UCNPs).
  • To investigate the mechanism behind the enhanced blue emission of the CSS UCNPs.
  • To develop a fluorescence resonance energy transfer (FRET)-based nanosensing platform using CSS UCNPs for the sensitive detection of ascorbic acid (AA).

Main Methods:

  • Synthesis of NaYbF4@NaYF4:2%Ho@NaYF4 (CSS) UCNPs with a core-shell structure.
  • Characterization of UCNP properties, including blue emission intensity and mechanisms.
  • Development of a FRET-based sensing system utilizing CSS UCNPs as donors and MnO2 nanosheets as acceptors for AA detection.

Main Results:

  • The CSS UCNPs exhibited significantly enhanced blue emission compared to control UCNPs.
  • The enhanced blue emission was attributed to protected NaYbF4 core, spatial separation of Yb3+ and Ho3+, and an inert shell.
  • A sensitive AA detection platform was established with a detection limit of 0.75 μM and a detection range of 0.5-100 μM.

Conclusions:

  • The study successfully explored the blue emission mechanism of Ho3+ in UCNPs.
  • A novel CSS/MnO2-based nanosensing platform was constructed for rapid and sensitive AA detection.
  • The developed UCNPs and sensing platform show promising applications in biochemical sensing and detection.