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Reference values in the nineties: from theory to practice?

N Montalbetti1

  • 1Laboratory of Clinical Biochemistry and Haematology, Ospedale Niguarda Ca Granda, Milano.

Annali Dell'Istituto Superiore Di Sanita
|January 1, 1991
PubMed
Summary
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Implementing the theory of reference values in clinical labs is challenging. Cooperative efforts and biological material banks can improve the availability and reduce the cost of reference values.

Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Reference Value Theory

Background:

  • Published literature on reference value theory is summarized.
  • Current practical implementation in clinical laboratories remains limited.

Purpose of the Study:

  • To discuss the reasons for the limited practical implementation of reference value theory.
  • To propose solutions for overcoming implementation challenges.

Main Methods:

  • Review of existing literature on reference value theory.
  • Discussion of practical challenges and potential solutions.

Main Results:

  • Limited implementation is due to difficulties in obtaining adequate reference sample groups.

Related Experiment Videos

  • Cooperative efforts are suggested to overcome these difficulties.
  • Ensuring stability and homogeneity of analytical quality and reference population is crucial.

    • Conclusions:

    • Cooperative efforts, adhering to strict quality requirements, can facilitate the implementation of reference value theory.
    • Biological material banks can simplify and lower the cost of producing reference values.