Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A radiopharmaceutical enhances CAR T cells against radio-sensitive and radio-resistant neuroblastoma by tumor sensitization and TME remodeling.

Cell reports. Medicine·2026
Same author

Development of novel GPC2-directed radiotheranostics and CAR T cell therapy for neuroblastoma.

Molecular therapy : the journal of the American Society of Gene Therapy·2026
Same author

Ablation of glypican-3 enhances radiosensitivity in liver cancer by prolonging G2/M arrest and activating the ATM/CHK2 pathway.

bioRxiv : the preprint server for biology·2026
Same author

T-Cell Clonal Expansion in Peripheral Blood Following Interventional Radiology Procedures for Metastatic Liver Cancer.

Cancers·2026
Same author

Targeted cellular micropharmacies deliver therapeutic agents to the brain.

EMBO molecular medicine·2026
Same author

A Novel CD147-Targeting Nanobody for Immuno-PET Imaging of Liver Cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Lipid-based nanocarriers as transformative treatment in tuberculosis: a systematic review of therapeutic efficacy.

Nanomedicine (London, England)·2026
Same journal

UCMSC-Exo for chemotherapy-induced myelosuppression in acute myeloid leukemia: a phase I clinical trial protocol.

Nanomedicine (London, England)·2026
Same journal

Aptamer-functionalized nanoparticles for cancer targeting: conjugation strategies, current applications and future perspectives.

Nanomedicine (London, England)·2026
Same journal

Targeted therapy of highly aggressive thyroid papillary carcinoma by AS1411-guided nanomaterials.

Nanomedicine (London, England)·2026
Same journal

Impacts of curcumin nanoemulgel on cell viability and apoptotic pathways: a comprehensive study of ROS generation across different skin cancer cell lines.

Nanomedicine (London, England)·2026
Same journal

Advancements in single-chain antibody functionalized nanoparticles for the treatment of advanced solid tumors.

Nanomedicine (London, England)·2026
See all related articles

Related Experiment Video

Updated: Dec 28, 2025

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods
09:23

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Published on: October 10, 2025

1.3K

Targeted nanomaterials for radiotherapy.

Freddy E Escorcia1, Michael R McDevitt, Carlos H Villa

  • 1Memorial Sloan Kettering Cancer Center, Molecular Pharmacology and Chemistry Program, New York, NY 10021, USA.

Nanomedicine (London, England)
|December 22, 2007
PubMed
Summary
This summary is machine-generated.

Nanomaterials are emerging as advanced drug-delivery systems for targeted cancer radiotherapy. These carbon-based nanoparticles can be engineered to deliver therapeutic radioisotopes directly to cancer cells.

More Related Videos

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.4K
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

8.5K

Related Experiment Videos

Last Updated: Dec 28, 2025

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods
09:23

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Published on: October 10, 2025

1.3K
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.4K
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

8.5K

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Oncology

Background:

  • Nanomaterials are increasingly recognized for their potential as therapeutic drug-delivery vehicles.
  • Existing nanomaterials include carbon-based particles (fullerenes, nanotubes), dendrimers, liposomes, and polymers.
  • These materials can be functionalized with ligands like antibodies and peptides for targeted delivery.

Purpose of the Study:

  • To review common nanomaterials investigated for drug delivery.
  • To discuss current and future applications of nanomaterials as drug-delivery scaffolds.
  • To emphasize the role of nanomaterials in targeted cancer radiotherapy.

Main Methods:

  • Review of existing literature on nanomaterials for drug delivery.
  • Analysis of ligand-based targeting strategies for cancer cells.
  • Examination of radioisotope delivery mechanisms using nanomaterials.

Main Results:

  • Various nanomaterials show promise for targeted drug delivery.
  • Ligand functionalization enables specific interaction with tumor antigens and vascular epitopes.
  • Nanomaterials can effectively deliver radioisotopes for cancer treatment.

Conclusions:

  • Nanomaterials represent a significant advancement in targeted cancer radiotherapy.
  • Further research into these drug-delivery scaffolds will enhance cancer treatment efficacy.
  • The targeted delivery of radioisotopes by nanomaterials offers a promising therapeutic strategy.